The number of international benchmarking competitions is steadily increasing in various fields of machine learning (ML) research and practice. So far, however, little is known about the common practice as well as bottlenecks faced by the community in tackling the research questions posed. To shed light on the status quo of algorithm development in the specific field of biomedical imaging analysis, we designed an international survey that was issued to all participants of challenges conducted in conjunction with the IEEE ISBI 2021 and MICCAI 2021 conferences (80 competitions in total). The survey covered participants' expertise and working environments, their chosen strategies, as well as algorithm characteristics. A median of 72% challenge participants took part in the survey. According to our results, knowledge exchange was the primary incentive (70%) for participation, while the reception of prize money played only a minor role (16%). While a median of 80 working hours was spent on method development, a large portion of participants stated that they did not have enough time for method development (32%). 25% perceived the infrastructure to be a bottleneck. Overall, 94% of all solutions were deep learning-based. Of these, 84% were based on standard architectures. 43% of the respondents reported that the data samples (e.g., images) were too large to be processed at once. This was most commonly addressed by patch-based training (69%), downsampling (37%), and solving 3D analysis tasks as a series of 2D tasks. K-fold cross-validation on the training set was performed by only 37% of the participants and only 50% of the participants performed ensembling based on multiple identical models (61%) or heterogeneous models (39%). 48% of the respondents applied postprocessing steps.

如今，随着发现的OSS漏洞的数量，开源软件（OSS）漏洞管理流程随着时间的流逝而增加。监视漏洞固定提交是防止脆弱性开发的标准过程的一部分。但是，由于可能有大量的审查，手动检测漏洞固定的犯罪是耗时的。最近，已经提出了许多技术来自动检测使用机器学习的漏洞固定提交。这些解决方案要么：（1）不使用深度学习，或（2）仅对有限的信息来源使用深度学习。本文提出了藤条，该工具利用了更丰富的信息来源，包括提交消息，代码更改和针对漏洞固定的提交分类的报告。我们的实验结果表明，在F1得分方面，沃尔维尔剂的表现优于最先进的基线。 Vulcurator工具可在https://github.com/ntgiang71096/vfdetector和https://zenodo.org/record/7034132#.yw3mn-xbzdi上公开获得。

构建静态呼叫图需要在健全和精度之间进行权衡。不幸的是，用于构建呼叫图的程序分析技术通常不精确。为了解决这个问题，研究人员最近提出了通过机器学习为静态分析构建的后处理呼叫图所授权的呼叫图。机器学习模型的构建是为了通过在随机森林分类器中提取结构特征来捕获呼叫图中的信息。然后，它消除了预测为误报的边缘。尽管机器学习模型显示了改进，但它们仍然受到限制，因为它们不考虑源代码语义，因此通常无法有效地区分真实和误报。在本文中，我们提出了一种新颖的呼叫图修剪技术AutoRoprouner，用于通过统计语义和结构分析消除呼叫图中的假阳性。给定一个由传统静态分析工具构建的呼叫图，AutoProuner采用基于变压器的方法来捕获呼叫者与呼叫图中每个边缘相关的呼叫者和Callee函数之间的语义关系。为此，AutoProuner微型调节模型是在大型语料库上预先训练的代码模型，以根据其语义的描述表示源代码。接下来，该模型用于从与呼叫图中的每个边缘相关的功能中提取语义特征。 AutoProuner使用这些语义功能以及从呼叫图提取的结构特征通过馈送前向神经网络分类。我们在现实世界程序的基准数据集上进行的经验评估表明，AutoProuner的表现优于最先进的基线，从而改善了F量级，在识别静态呼叫图中识别错误阳性边缘方面，高达13％。

Automatically generated static code warnings suffer from a large number of false alarms. Hence, developers only take action on a small percent of those warnings. To better predict which static code warnings should not be ignored, we suggest that analysts need to look deeper into their algorithms to find choices that better improve the particulars of their specific problem. Specifically, we show here that effective predictors of such warnings can be created by methods that locally adjust the decision boundary (between actionable warnings and others). These methods yield a new high water-mark for recognizing actionable static code warnings. For eight open-source Java projects (cassandra, jmeter, commons, lucene-solr, maven, ant, tomcat, derby) we achieve perfect test results on 4/8 datasets and, overall, a median AUC (area under the true negatives, true positives curve) of 92%.

Deep learning has been widely used for protein engineering. However, it is limited by the lack of sufficient experimental data to train an accurate model for predicting the functional fitness of high-order mutants. Here, we develop SESNet, a supervised deep-learning model to predict the fitness for protein mutants by leveraging both sequence and structure information, and exploiting attention mechanism. Our model integrates local evolutionary context from homologous sequences, the global evolutionary context encoding rich semantic from the universal protein sequence space and the structure information accounting for the microenvironment around each residue in a protein. We show that SESNet outperforms state-of-the-art models for predicting the sequence-function relationship on 26 deep mutational scanning datasets. More importantly, we propose a data augmentation strategy by leveraging the data from unsupervised models to pre-train our model. After that, our model can achieve strikingly high accuracy in prediction of the fitness of protein mutants, especially for the higher order variants (> 4 mutation sites), when finetuned by using only a small number of experimental mutation data (<50). The strategy proposed is of great practical value as the required experimental effort, i.e., producing a few tens of experimental mutation data on a given protein, is generally affordable by an ordinary biochemical group and can be applied on almost any protein.

We introduce TeSS (Text Similarity Comparison using Sentence Encoder), a framework for zero-shot classification where the assigned label is determined by the embedding similarity between the input text and each candidate label prompt. We leverage representations from sentence encoders optimized to locate semantically similar samples closer to each other in embedding space during pre-training. The label prompt embeddings serve as prototypes of their corresponding class clusters. Furthermore, to compensate for the potentially poorly descriptive labels in their original format, we retrieve semantically similar sentences from external corpora and additionally use them with the original label prompt (TeSS-R). TeSS outperforms strong baselines on various closed-set and open-set classification datasets under zero-shot setting, with further gains when combined with label prompt diversification through retrieval. These results are robustly attained to verbalizer variations, an ancillary benefit of using a bi-encoder. Altogether, our method serves as a reliable baseline for zero-shot classification and a simple interface to assess the quality of sentence encoders.

Previous video-based human pose estimation methods have shown promising results by leveraging aggregated features of consecutive frames. However, most approaches compromise accuracy to mitigate jitter or do not sufficiently comprehend the temporal aspects of human motion. Furthermore, occlusion increases uncertainty between consecutive frames, which results in unsmooth results. To address these issues, we design an architecture that exploits the keypoint kinematic features with the following components. First, we effectively capture the temporal features by leveraging individual keypoint's velocity and acceleration. Second, the proposed hierarchical transformer encoder aggregates spatio-temporal dependencies and refines the 2D or 3D input pose estimated from existing estimators. Finally, we provide an online cross-supervision between the refined input pose generated from the encoder and the final pose from our decoder to enable joint optimization. We demonstrate comprehensive results and validate the effectiveness of our model in various tasks: 2D pose estimation, 3D pose estimation, body mesh recovery, and sparsely annotated multi-human pose estimation. Our code is available at https://github.com/KyungMinJin/HANet.

Image super-resolution is a common task on mobile and IoT devices, where one often needs to upscale and enhance low-resolution images and video frames. While numerous solutions have been proposed for this problem in the past, they are usually not compatible with low-power mobile NPUs having many computational and memory constraints. In this Mobile AI challenge, we address this problem and propose the participants to design an efficient quantized image super-resolution solution that can demonstrate a real-time performance on mobile NPUs. The participants were provided with the DIV2K dataset and trained INT8 models to do a high-quality 3X image upscaling. The runtime of all models was evaluated on the Synaptics VS680 Smart Home board with a dedicated edge NPU capable of accelerating quantized neural networks. All proposed solutions are fully compatible with the above NPU, demonstrating an up to 60 FPS rate when reconstructing Full HD resolution images. A detailed description of all models developed in the challenge is provided in this paper.

For ensuring vehicle safety, the impact performance of wheels during wheel development must be ensured through a wheel impact test. However, manufacturing and testing a real wheel requires a significant time and money because developing an optimal wheel design requires numerous iterative processes to modify the wheel design and verify the safety performance. Accordingly, wheel impact tests have been replaced by computer simulations such as finite element analysis (FEA); however, it still incurs high computational costs for modeling and analysis, and requires FEA experts. In this study, we present an aluminum road wheel impact performance prediction model based on deep learning that replaces computationally expensive and time-consuming 3D FEA. For this purpose, 2D disk-view wheel image data, 3D wheel voxel data, and barrier mass values used for the wheel impact test were utilized as the inputs to predict the magnitude of the maximum von Mises stress, corresponding location, and the stress distribution of the 2D disk-view. The input data were first compressed into a latent space with a 3D convolutional variational autoencoder (cVAE) and 2D convolutional autoencoder (cAE). Subsequently, the fully connected layers were used to predict the impact performance, and a decoder was used to predict the stress distribution heatmap of the 2D disk-view. The proposed model can replace the impact test in the early wheel-development stage by predicting the impact performance in real-time and can be used without domain knowledge. The time required for the wheel development process can be reduced by using this mechanism.

ICECUBE是一种用于检测1 GEV和1 PEV之间大气和天体中微子的光学传感器的立方公斤阵列，该阵列已部署1.45 km至2.45 km的南极的冰盖表面以下1.45 km至2.45 km。来自ICE探测器的事件的分类和重建在ICeCube数据分析中起着核心作用。重建和分类事件是一个挑战，这是由于探测器的几何形状，不均匀的散射和冰中光的吸收，并且低于100 GEV的光，每个事件产生的信号光子数量相对较少。为了应对这一挑战，可以将ICECUBE事件表示为点云图形，并将图形神经网络（GNN）作为分类和重建方法。 GNN能够将中微子事件与宇宙射线背景区分开，对不同的中微子事件类型进行分类，并重建沉积的能量，方向和相互作用顶点。基于仿真，我们提供了1-100 GEV能量范围的比较与当前ICECUBE分析中使用的当前最新最大似然技术，包括已知系统不确定性的影响。对于中微子事件分类，与当前的IceCube方法相比，GNN以固定的假阳性速率（FPR）提高了信号效率的18％。另外，GNN在固定信号效率下将FPR的降低超过8（低于半百分比）。对于能源，方向和相互作用顶点的重建，与当前最大似然技术相比，分辨率平均提高了13％-20％。当在GPU上运行时，GNN能够以几乎是2.7 kHz的中位数ICECUBE触发速率的速率处理ICECUBE事件，这打开了在在线搜索瞬态事件中使用低能量中微子的可能性。